Sam (Hugh Laurie) and Lucy Bell (Joely Richardson) are a married couple who seem to have it all: good looks, successful careers, matching motorbikes, and an enthusiastic love life. The only thing they lack is the one thing they want most - a baby. They try everything everywhere in their efforts to reproduce. Spontaneity is soon replaced by ovulation charts, and when the couple seeks medical help they soon find themselves bound to sperm tests and stirrups. Sam looks to break out of the doldrums by writing a successful screenplay, and his inspiration for the piece is a comedy about a couple trying to have a baby. Horrified by the idea, Lucy forbids him to tell their story. The prospect for creative fulfillment is too tempting for Sam to resist, and he goes ahead with the project. Meanwhile, Lucy is distracted by the attentions of a handsome client. Sam and Lucy's love for each other will now truly be put to the ultimate test…with surprising results!